The Krause end bulb, also known as the Krause corpuscle or bulboid corpuscle, is a sensory receptor found in several parts of the body, including the skin, mucous membranes, and hair follicles. It is named after its discoverer, German anatomist Johannes Peter Müller Krause.
The Krause end bulb is a type of encapsulated nerve ending, which means that it is surrounded by a capsule that protects it from damage. The capsule contains several layers of connective tissue and supports a network of axons that carry sensory information to the brain.
Krause end bulbs are sensitive to cold temperatures and light touch. They play an important role in the perception of temperature and texture, as well as in the regulation of body temperature and blood flow.
Krause end bulbs are most commonly found in areas that are exposed to the cold, such as the fingertips, nose, and lips. However, they are also found in other areas of the body, including the genitalia, tongue, and joints.
Some disorders and injuries can damage or destroy the Krause end bulbs, leading to sensory loss or dysfunction. For example, peripheral neuropathies, autoimmune diseases, and certain viral infections can cause damage to sensory nerves and their associated receptors.
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